Invention Grant
US09453038B2 Glucokinase activator compounds, compositions containing such compounds, and methods of treatment
有权
葡糖激酶活化剂化合物，含有这些化合物的组合物和治疗方法
- Patent Title: Glucokinase activator compounds, compositions containing such compounds, and methods of treatment
- Patent Title (中): 葡糖激酶活化剂化合物，含有这些化合物的组合物和治疗方法
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Application No.: US14652883Application Date: 2013-12-12
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Publication No.: US09453038B2Publication Date: 2016-09-27
- Inventor: Songnian Lin , Rui Zhang , Brian Campbell , Sunita V. Dewnani , Jiayi Xu , Libo Xu , Emma R. Parmee , Roman Kats-Kagan
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Anna L. Cocuzzo; Catherine D. Fitch
- International Application: PCT/US2013/074574 WO 20131212
- International Announcement: WO2014/099578 WO 20140626
- Main IPC: C07F9/6539
- IPC: C07F9/6539 ; A61K31/4439 ; C07D401/04 ; A61K31/444 ; C07D471/04 ; A61K31/437 ; C07F9/58 ; A61K31/675 ; A61K31/497 ; A61K31/427 ; C07F9/6558 ; C07F7/08 ; C07D401/14 ; C07D403/04 ; C07D403/14 ; C07D417/14
Abstract:
Novel pyridine-2-carboxamide derivatives of formula I: and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. The compounds are effective as glucokinase activating agents. Pharmaceutical compositions and methods of treatment are also included.
Public/Granted literature
- US20150336991A1 NOVEL GLUCOKINASE ACTIVATOR COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF TREATMENT Public/Granted day:2015-11-26
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