Methods, systems, and media for providing determinism in multithreaded programs are provided. In some embodiments, methods for providing determinism in multithreaded programs are provided, the methods comprising: instrumenting a program with: a proxy that: receives inputs to the program; and determines whether a schedule corresponding to a set of input constraints satisfied by the inputs has been memoized; and a replayer that: if it is determined that a schedule corresponding to a set of input constraints satisfied by the inputs has been memoized, processes the inputs by the program according to the schedule.