发明授权
- 专利标题: Calcium flux agonists and methods thereof
- 专利标题(中): 钙通量激动剂及其方法
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申请号: US14442392申请日: 2013-11-13
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公开(公告)号: US09463184B2公开(公告)日: 2016-10-11
- 发明人: Kayvan Niazi , Shahrooz Rabizadeh , Justin Golovato , Patrick Soon-Shiong , Anne-Laure Le Ny , Oleksandr Buzko
- 申请人: Nant Holdings IP, LLC
- 申请人地址: US CA Culver City
- 专利权人: Nant Holdings IP, LLC
- 当前专利权人: Nant Holdings IP, LLC
- 当前专利权人地址: US CA Culver City
- 代理机构: Fish & Tsang, LLP
- 国际申请: PCT/US2013/069939 WO 20131113
- 国际公布: WO2014/078447 WO 20140522
- 主分类号: A01N43/76
- IPC分类号: A01N43/76 ; A61K31/42 ; A01N43/08 ; A61K31/34 ; A01N43/20 ; A01N43/24 ; A61K31/335 ; A61K31/423 ; A61K31/05 ; A61K31/12 ; A61K31/365 ; A61K31/404 ; A61K31/407 ; A61K33/24 ; A61K9/00 ; A61K47/06 ; A61K47/10 ; A61K31/341 ; A61K31/16 ; A61K31/66
摘要:
Calcium flux agonists are used to enhance a TLR- or NOD-mediated stimulus and to so increase an immune response of a host and reduce healing time. Preferred calcium flux agonists include Ca2+ ionophores and SERCA inhibitors and are used in synergistic quantities where a ligand to a TLR or NOD receptor is present.
公开/授权文献
- US20150297572A1 Calcium Flux Agonists And Methods Therefor 公开/授权日:2015-10-22
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