Invention Grant
- Patent Title: 5-oxo-ETE receptor antagonist compounds
- Patent Title (中): 5-氧代-ETE受体拮抗剂化合物
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Application No.: US14324579Application Date: 2014-07-07
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Publication No.: US09464048B2Publication Date: 2016-10-11
- Inventor: William S. Powell , Joshua Rokach
- Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY , FLORIDA INSTITUTE OF TECHNOLOGY
- Applicant Address: US FL Melbourne CA Montreal, Quebec
- Assignee: Florida Institute of Technology,The Royal Institution for the Advancement of Learning/McGill University
- Current Assignee: Florida Institute of Technology,The Royal Institution for the Advancement of Learning/McGill University
- Current Assignee Address: US FL Melbourne CA Montreal, Quebec
- Agency: Buchanan Ingersoll & Rooney P.C.
- Main IPC: C07D209/12
- IPC: C07D209/12 ; C07D403/06 ; C07D209/18 ; C07C59/84 ; C07D209/08 ; C07D209/10 ; C07D209/24 ; C07D215/12 ; C07D235/08 ; C07D307/79

Abstract:
The present invention relates to novel pharmaceutically-useful compounds which are antagonists of the 5-oxo-ETE receptors, such as the OXE receptor. These compounds have use as therapeutic and/or prophylactic agents for diseases characterized by tissue eosinophilia, such as inflammatory conditions including respiratory diseases. The invention also relates to pharmaceutical compositions, to the use of such compounds and compositions as medicaments, and to therapeutic methods.
Public/Granted literature
- US20140323535A1 5-OXO-ETE RECEPTOR ANTAGONIST COMPOUNDS Public/Granted day:2014-10-30
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