发明授权
US09464135B2 Epithelial membrane protein-2 (EMP2) and proliferative vitroretinopathy (PVR)
有权
上皮膜蛋白-2(EMP2)和增殖性视网膜病变(PVR)
- 专利标题: Epithelial membrane protein-2 (EMP2) and proliferative vitroretinopathy (PVR)
- 专利标题(中): 上皮膜蛋白-2(EMP2)和增殖性视网膜病变(PVR)
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申请号: US13510877申请日: 2010-11-18
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公开(公告)号: US09464135B2公开(公告)日: 2016-10-11
- 发明人: Lynn K. Gordon , Shawn A. Morales , David Telander , Jonathan Braun
- 申请人: Lynn K. Gordon , Shawn A. Morales , David Telander , Jonathan Braun
- 申请人地址: US CA Oakland US DC Washington
- 专利权人: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA,THE UNITED STATES OF AMERICA DEPARTMENT OF VETERAN AFFAIRS
- 当前专利权人: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA,THE UNITED STATES OF AMERICA DEPARTMENT OF VETERAN AFFAIRS
- 当前专利权人地址: US CA Oakland US DC Washington
- 代理机构: Morgan, Lewis & Bockius LLP
- 代理商 Jeffry S. Mann
- 国际申请: PCT/US2010/057296 WO 20101118
- 国际公布: WO2011/063161 WO 20110526
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61K9/48 ; A61K47/48 ; A61K9/51 ; C07K16/28 ; A61K9/00 ; A61K39/00
摘要:
Methods of preventing retinal detachment associated with proliferative vitreoretinopathy are provided by administering agents which antagonize the activity or function of EMP2 to subjects at risk of the detachment.
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