A packaging method and a display device are provided. The packaging method comprise: providing a first substrate and a second substrate having a packaging region, wherein a region surrounding by the packaging region of the second substrate is provided with a device to be packaged; forming a pattern layer of sealant on the packaging region of the first substrate; bonding the first substrate having the sealant with the second substrate having a device to be packaged so that the packaging region of the first substrate is aligned with the packaging region of the second substrate; and sintering the sealant and applying uniformly a compression force to the packaging region when using a laser to radiate the packaging region.