Invention Grant
US09474792B2 Method of treating metabolic disorders using PLA2G12A polypeptides and PLA2G12A mutant polypeptides
有权
使用PLA2G12A多肽和PLA2G12A突变体多肽治疗代谢紊乱的方法
- Patent Title: Method of treating metabolic disorders using PLA2G12A polypeptides and PLA2G12A mutant polypeptides
- Patent Title (中): 使用PLA2G12A多肽和PLA2G12A突变体多肽治疗代谢紊乱的方法
-
Application No.: US14772910Application Date: 2014-03-13
-
Publication No.: US09474792B2Publication Date: 2016-10-25
- Inventor: Daniel C. H. Lin , Jinghong Wang , Yang Li
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- International Application: PCT/US2014/026736 WO 20140313
- International Announcement: WO2014/151962 WO 20140925
- Main IPC: A61K38/46
- IPC: A61K38/46 ; A61B5/145 ; C12N9/20
Abstract:
Methods of treating or ameliorating metabolic diseases using a PLA2G12A polypeptide or PLA2G12A mutant polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes mellitus, obesity, dyslipidemia elevated glucose levels, elevated insulin levels and diabetic nephropathy.
Public/Granted literature
- US20160008439A1 Method of Treating Metabolic Disorders Using PLA2G12A Polypeptides and PLA2G12A Mutant Polypeptides Public/Granted day:2016-01-14
Information query
IPC分类:
