A system for controlling an air flow in a vehicle may include a front air introduction apparatus mounted in front of an engine, a condenser provided to the front air introduction apparatus, an intercooler provided behind the condenser, a radiator provided between the intercooler and the engine, an active air flap for controlling air flow being introduced to the front air introduction apparatus, a side air introduction apparatus mounted to a side of an engine compartment for forwarding air to the engine, a connection line connected between the side air introduction apparatus and the front air introduction apparatus, a control valve for controlling air flow through the connection line, a plurality of sensors for measuring an operation state of the vehicle, and a control unit for determining an operation state of the vehicle based on a plurality of sensor signals, and controlling operation of the control valve.