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Invention Grant
US09481688B2 (Thieno[2,3-b][1,5]benzoxazepin-4-yl)piperazin-1-yl compounds as dual activity H1 inverse agonists/5-HT2A antagonists 有权
（噻吩并[2,3-b] [1,5]苯并氧氮杂-4-基）哌嗪-1-基化合物作为双重活性H1反向激动剂/ 5-HT2A拮抗剂

  • Patent Title: (Thieno[2,3-b][1,5]benzoxazepin-4-yl)piperazin-1-yl compounds as dual activity H1 inverse agonists/5-HT2A antagonists
  • Patent Title (中): （噻吩并[2,3-b] [1,5]苯并氧氮杂-4-基）哌嗪-1-基化合物作为双重活性H1反向激动剂/ 5-HT2A拮抗剂
  • Application No.: US14125320
    Application Date: 2012-07-02
  • Publication No.: US09481688B2
    Publication Date: 2016-11-01
  • Inventor: Andrew James Ledgard
  • Applicant: Andrew James Ledgard
  • Applicant Address: US IN Indianapolis
  • Assignee: Eli Lilly and Company
  • Current Assignee: Eli Lilly and Company
  • Current Assignee Address: US IN Indianapolis
  • Agent R. Craig Tucker
  • International Application: PCT/US2012/045254 WO 20120702
  • International Announcement: WO2013/009517 WO 20130117
  • Main IPC: A61K31/553
  • IPC: A61K31/553 ;  C07D498/04 ;  A61K45/06
(Thieno[2,3-b][1,5]benzoxazepin-4-yl)piperazin-1-yl compounds as dual activity H1 inverse agonists/5-HT2A antagonists
Abstract:
A dual H1/5-HT2A receptor antagonist of the formula: its uses, and methods for its preparation are described.
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