发明授权
- 专利标题: DR5—FAP bispecific death receptor agonistic antibodies
- 专利标题(中): DR5-FAP双特异性死亡受体激动抗体
-
申请号: US13498390申请日: 2010-09-27
-
公开(公告)号: US09481730B2公开(公告)日: 2016-11-01
- 发明人: Peter Bruenker , Claudia Ferrara Koller , Sandra Grau , Sylvia Herter , Christoph Lampert , Ekkehard Moessner , Pablo Umana , Inja Waldhauer
- 申请人: Peter Bruenker , Claudia Ferrara Koller , Sandra Grau , Sylvia Herter , Christoph Lampert , Ekkehard Moessner , Pablo Umana , Inja Waldhauer
- 申请人地址: CH Schlieren
- 专利权人: Roche Glycart AG
- 当前专利权人: Roche Glycart AG
- 当前专利权人地址: CH Schlieren
- 优先权: EP09171659 20090929
- 国际申请: PCT/EP2010/064209 WO 20100927
- 国际公布: WO2011/039126 WO 20110407
- 主分类号: C07K16/30
- IPC分类号: C07K16/30 ; C07K16/28 ; C07K16/18 ; C07K16/40 ; C07K14/715 ; C12N9/00
摘要:
The present invention relates to bispecific antibodies comprising a first antigen binding site specific for a death receptor and a second antigen binding site specific for a second antigen, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
公开/授权文献
- US20120184718A1 BISPECIFIC DEATH RECEPTOR AGONISTIC ANTIBODIES 公开/授权日:2012-07-19
信息查询