An after-treatment system for treating exhaust gas discharged from a combustion engine, the after-treatment system comprising an exhaust after-treatment component including an exhaust after-treatment substrate, the exhaust after-treatment substrate including an inlet face including a first zone having a first catalyst located at a center of the inlet face, and a second zone having a second catalyst located radially outward from the center of the inlet face, wherein an amount of the exhaust gas that travels through the first zone is greater than an amount of the exhaust gas that passes through the second zone, and a catalyst loading of the first catalyst in the first zone is less than a catalyst loading of the second catalyst in the second zone.