Provided are methods and systems for calibrating a distributed sensor (e.g., microphone) array using time-of-flight (TOF) measurements for a plurality of spatially distributed acoustic events at the sensors. The calibration includes localization and gain equalization of the sensors. Accurate measurements of TOFs are obtained from spatially distributed acoustic events using a controlled signal emitted at known intervals by a moving acoustic source. A portable user device capable of playing out audio is used to produce a plurality of acoustic events (e.g., sound clicks) at known intervals of time and at different, but arbitrary locations based on the device being moved around in space by a user while producing the acoustic events. As such, the times of the acoustic event generation are known, and are spatially diverse. The calibration signals emitted by the acoustic source are designed to provide robustness to noise and reverberation.