Invention Grant
US09498452B2 Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine
有权
用反式4-（3,4-二氯苯基）-1,2,3,4-四氢-1-萘胺处理CNS病症
- Patent Title: Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine
- Patent Title (中): 用反式4-（3,4-二氯苯基）-1,2,3,4-四氢-1-萘胺处理CNS病症
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Application No.: US14727260Application Date: 2015-06-01
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Publication No.: US09498452B2Publication Date: 2016-11-22
- Inventor: Thomas Jerussi , Qun Kevin Fang , Mark G. Currie
- Applicant: SUNOVION PHARMACEUTICALS INC.
- Applicant Address: US MA Marlborough
- Assignee: Sunovion Pharmaceuticals Inc.
- Current Assignee: Sunovion Pharmaceuticals Inc.
- Current Assignee Address: US MA Marlborough
- Agency: Heslin, Rothenberg, Farley & Mesiti P.C.
- Main IPC: A61K31/135
- IPC: A61K31/135 ; C07C211/42
Abstract:
Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
Public/Granted literature
- US20160136111A1 TREATMENT OF CNS DISORDERS WITH trans 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE Public/Granted day:2016-05-19
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