An apparatus and a method for combining three-dimensional ultrasound images are provide. The method involves obtaining a plurality of three-dimensional ultrasound image data that corresponds to a Region of Interest (ROI); detecting one or more landmarks, using a parameter for detection; outputting the detection result and receiving a response from a user; registering each of one or more selected landmarks as link information according to a received response from the user; and generating a combined three-dimensional ultrasound image by combining at least two pieces of three-dimensional ultrasound image data using at least one of the one or more selected landmarks registered as the link information, wherein the at least two pieces of three-dimensional ultrasound image data commonly comprise the at least one of the one or more selected landmarks.