- 专利标题： Modifications for antisense compounds
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申请号： US13776397申请日： 2013-02-25
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公开(公告)号： US09506057B2公开(公告)日： 2016-11-29
- 发明人: Mark Aaron Behlke , Kimberly Ann Lennox , Ashley Mae Jacobi , Richard Owczarzy , Joseph Alan Walder
- 申请人： Integrated DNA Technologies, Inc.
- 申请人地址： US IA Coralville
- 专利权人： Integrated DNA Technologies, Inc.
- 当前专利权人： Integrated DNA Technologies, Inc.
- 当前专利权人地址： US IA Coralville
- 代理机构： McDonnell Boehnen Hulbert & Berghoff LLP
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; C12N15/113
摘要：
The invention pertains to modifications for antisense oligonucleotides, wherein the modifications are used to improve stability and provide protection from nuclease degradation. The modifications could also be incorporated into double-stranded nucleic acids, such as synthetic siRNAs and miRNAs.
公开/授权文献
- US20130236967A1 Modifications for Antisense Compounds 公开/授权日：2013-09-12
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