A flow regulating device 1 is provided which includes: a housing 10c including a pressure chamber 12 formed therein; a second housing 10b including a first space 22 formed therein; a valve element 31 which forms a closed state in which communication is shut off between an upstream flow channel 15 and a downstream flow channel 16, or an open state in which communication is provided between the upstream flow channel 15 and a downstream flow channel 16; a diaphragm 35 connected to the valve element 31; a guide member 42 connected to the diaphragm 35 which is movable in an axial direction of the valve element 31 with the movement of the valve element 31 while being in a state in which the guide member 42 is in contact with an inner circumferential surface of the pressure chamber 12.