发明授权
US09518008B2 (1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-uanidino-2-hydroxyl-cyclopentyl-1-carboxylic acid hydrates pharmaceutical uses thereof
有权
（1S，2S，3S，4R）-3 - [（1S）-1-乙酰氨基-2-乙基 - 丁基] -4- uan基-2-羟基 - 环戊基-1-羧酸水合物
![(1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-uanidino-2-hydroxyl-cyclopentyl-1-carboxylic acid hydrates pharmaceutical uses thereof](/docs/US/2016-12-13/US09518008B2/abs.jpg.600x600.jpg)
- 专利标题： (1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-uanidino-2-hydroxyl-cyclopentyl-1-carboxylic acid hydrates pharmaceutical uses thereof
- 专利标题（中）： （1S，2S，3S，4R）-3 - [（1S）-1-乙酰氨基-2-乙基 - 丁基] -4- uan基-2-羟基 - 环戊基-1-羧酸水合物
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申请号： US14511783申请日： 2014-10-10
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公开(公告)号： US09518008B2公开(公告)日： 2016-12-13
- 发明人: Song Li , Wu Zhong , Zhibing Zheng , Xinbo Zhou , Junhai Xiao , Yunde Xie , Lili Wang , Xingzhou Li , Guoming Zhao , Xiaokui Wang , Hongying Liu
- 申请人： Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A., China
- 申请人地址： CN Beijing
- 专利权人： Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A., China
- 当前专利权人： Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A., China
- 当前专利权人地址： CN Beijing
- 代理机构： Brinks Gilson & Lione
- 优先权： CN200710143607 20070814
- 主分类号： A61K31/196
- IPC分类号： A61K31/196 ; C07C279/16 ; C07C277/08 ; A61P31/16 ; C07C277/06
![(1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-uanidino-2-hydroxyl-cyclopentyl-1-carboxylic acid hydrates pharmaceutical uses thereof](/abs-image/US/2016/12/13/US09518008B2/abs.jpg.150x150.jpg)
摘要：
The present invention relates to (1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-guanidino-2-hydroxy-cyclopentyl-1-carboxylic acid hydrates compounds, preparing methods thereof, pharmaceutical compositions containing said compounds and preparing methods thereof, and the clinical uses of said compounds as neuramidinase inhibitors for anti-influenza.
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