A touch screen sensing device includes a touch screen including touch sensors formed at crossings of Tx lines and Rx lines, a Tx driving circuit supplying a driving pulse to each of the Tx lines N times, and an Rx driving circuit which samples a signal voltage of the touch sensors received through the Rx lines and converts the sampled signal voltage into digital data. The Rx driving circuit includes a differential amplifier differentially amplifying signals received through the Rx lines, a low pass filter removing a radio frequency noise from an output of the differential amplifier, an amplifier amplifying an output of the low pass filter, and an integrator accumulating signal voltages which are successively output from the amplifier.