An air-conditioning apparatus uses R32, a refrigerant mixture containing R32 and HFO1234yf in which R32 has a mass percentage of 40% or higher, or a refrigerant mixture containing R32 and HFO1234ze in which R32 has a mass percentage of 15% or higher, as a heat-source refrigerant. The air-conditioning apparatus includes a low-pressure shell-structure compressor, a first flow switching valve, a heat-source-side heat exchanger, first flow control devices, and plural use-side heat exchangers connected by refrigerant pipes, forming a refrigeration cycle. The compressor includes a compression chamber within a sealed container including an opening extending between inside and outside of the sealed container. The air-conditioning apparatus can perform only a heating at the use-side heat exchangers, only a cooling at the use-side heat exchangers, and a mixed cooling and heating in a mixed fashion at the use-side heat exchangers.