发明授权
- 专利标题: Humanized monoclonal antibodies and methods of use
- 专利标题(中): 人源化单克隆抗体及其使用方法
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申请号: US13700974申请日: 2011-06-02
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公开(公告)号: US09527924B2公开(公告)日: 2016-12-27
- 发明人: Wayne A. Marasco , Jianhua Sui , Yuval Avnir
- 申请人: Wayne A. Marasco , Jianhua Sui , Yuval Avnir
- 申请人地址: US MA Boston
- 专利权人: DANA-FARBER CANCER INSTITUTE, INC.
- 当前专利权人: DANA-FARBER CANCER INSTITUTE, INC.
- 当前专利权人地址: US MA Boston
- 代理机构: Cooley LLP
- 代理商 Ivor Elrifi; Cynthia Kozakiewicz
- 国际申请: PCT/US2011/038970 WO 20110602
- 国际公布: WO2011/153380 WO 20111208
- 主分类号: C07K16/42
- IPC分类号: C07K16/42 ; A61K39/395 ; A61K39/145 ; C07K16/10 ; A61K39/00 ; A61K39/39
摘要:
Disclosed is a humanized monoclonal antibody that binds to the human immunoglobulin heavy chain variable region germline gene VHI-69. The antibody is derived from Mab G6 and recognizes the same epitope. Moreover, the antibody is used in combination with vaccines to augment an immune response to the antigen.
公开/授权文献
- US20130243749A1 Humanized Monoclonal Antibodies and Methods of Use 公开/授权日:2013-09-19
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