发明授权
- 专利标题: Methods of efficiently establishing induced pluripotent stem cells under hypoxic conditions
- 专利标题(中): 在缺氧条件下有效建立诱导多能干细胞的方法
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申请号: US12672222申请日: 2009-07-30
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公开(公告)号: US09528092B2公开(公告)日: 2016-12-27
- 发明人: Shinya Yamanaka , Yoshinori Yoshida
- 申请人: Shinya Yamanaka , Yoshinori Yoshida
- 申请人地址: JP Kyoto
- 专利权人: Kyoto University
- 当前专利权人: Kyoto University
- 当前专利权人地址: JP Kyoto
- 代理机构: Leydig, Voit & Mayer, Ltd.
- 国际申请: PCT/JP2009/063906 WO 20090730
- 国际公布: WO2010/013845 WO 20100204
- 主分类号: C12N15/87
- IPC分类号: C12N15/87 ; C12N5/074
摘要:
Provided is a method of improving the efficiency of establishment of induced pluripotent stem cells, comprising culturing somatic cells under hypoxic conditions in the step of nuclear reprogramming thereof.
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