The present disclosure relates to a gray-scale correction method of a display panel, comprising: selecting a plurality of measurement points and specifying a reference point; specifying a plurality of measurement gray-scales, and, under each measurement gray-scale, measuring actual gray-scale of each measurement point when the brightness thereof reaches a reference brightness, wherein the reference brightness is the brightness of the reference point; determining a gray-scale correction coefficient of each measurement point under each measurement gray-scale according to the corresponding relationship between the actual gray-scale and the measurement gray-scale, and establishing an original gray-scale correction coefficient table; extending the original gray-scale correction coefficient table to a gray-scale correction coefficient table of pixel points of the display panel under all gray-scales through linear interpolation algorithm; when a data voltage is to be applied to a pixel point under a gray-scale, searching the gray-scale correction coefficient corresponding to said gray-scale and said pixel point from the extended gray-scale correction coefficient table, correcting the value of said gray-scale accordingly, and driving the display panel according to the corrected gray-scale.