发明授权
- 专利标题: Cell lines expressing ENaC and methods using them
- 专利标题(中): 表达ENaC的细胞系和使用它们的方法
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申请号: US12864295申请日: 2009-01-25
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公开(公告)号: US09534035B2公开(公告)日: 2017-01-03
- 发明人: Kambiz Shekdar , Jessica Langer , Dennis Sawchuk
- 申请人: Kambiz Shekdar , Jessica Langer , Dennis Sawchuk
- 申请人地址: US NJ North Brunswick
- 专利权人: CHROMOCELL CORPORATION
- 当前专利权人: CHROMOCELL CORPORATION
- 当前专利权人地址: US NJ North Brunswick
- 代理机构: Ropes & Gray LLP
- 代理商 Brian M. Gummow; Sabine U Epelbaum
- 国际申请: PCT/US2009/031936 WO 20090125
- 国际公布: WO2009/094610 WO 20090730
- 主分类号: C40B30/06
- IPC分类号: C40B30/06 ; C07K14/705 ; G01N33/68
摘要:
Cell lines that stably express ENaC and methods for using those cell lines are disclosed herein. The invention includes cell lines that express various subunit combinations and various proteolyzed isoforms of ENaC and techniques for creating cell lines. The ENaC-expressing cell lines are highly sensitive, physiologically relevant and produce consistent results.
公开/授权文献
- US20100298167A1 NOVEL CELL LINES EXPRESSING ENAC AND METHODS USING THEM 公开/授权日:2010-11-25