It may be determined that a cloud desktop should be migrated from a current region. A destination region to which the cloud desktop will be migrated can be identified. A data volume of the cloud desktop may be copied from the current region to the destination region. The data volume at the current region and the data volume at the destination region may be maintained in sync during the copying. Upon completion of the copying, a current user session associated with the cloud desktop at the current region may be frozen, a current memory and processor state of the current user session may be copied to the destination region, and a second cloud desktop instance at the destination region may be started using the copied data volume and current memory and processor state. The current user session may be connected to the second cloud desktop instance.