Invention Grant
US09540398B2 3-(1h-imidazo[4,5-C]pyridin-2-yl)-1h-pyrazolo[3,4-C]pyridine and therapeutic uses thereof
有权
3-（1H-咪唑并[4,5-C]吡啶-2-基）-1H-吡唑并[3,4-C]吡啶及其治疗用途
![3-(1h-imidazo[4,5-C]pyridin-2-yl)-1h-pyrazolo[3,4-C]pyridine and therapeutic uses thereof](/docs/US/2017-01-10/US09540398B2/abs.jpg.600x600.jpg)
- Patent Title: 3-(1h-imidazo[4,5-C]pyridin-2-yl)-1h-pyrazolo[3,4-C]pyridine and therapeutic uses thereof
- Patent Title (中): 3-（1H-咪唑并[4,5-C]吡啶-2-基）-1H-吡唑并[3,4-C]吡啶及其治疗用途
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Application No.: US14847287Application Date: 2015-09-08
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Publication No.: US09540398B2Publication Date: 2017-01-10
- Inventor: Sunil Kumar KC , David Mark Wallace , Jianguo Cao , Chandramouli Chiruta , John Hood
- Applicant: Samumed, LLC
- Applicant Address: US CA San Diego
- Assignee: Samumed, LLC
- Current Assignee: Samumed, LLC
- Current Assignee Address: US CA San Diego
- Agency: Fish & Richardson P.C.
- Main IPC: A61K31/416
- IPC: A61K31/416 ; C07D519/00
![3-(1h-imidazo[4,5-C]pyridin-2-yl)-1h-pyrazolo[3,4-C]pyridine and therapeutic uses thereof](/abs-image/US/2017/01/10/US09540398B2/abs.jpg.150x150.jpg)
Abstract:
Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.
Public/Granted literature
- US20160068547A1 3-(1H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-C]PYRIDINE AND THERAPEUTIC USES THEREOF Public/Granted day:2016-03-10
Information query
IPC分类:
