发明授权
- 专利标题: MSP nanopores and related methods
- 专利标题(中): MSP纳米孔及相关方法
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申请号: US14993952申请日: 2016-01-12
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公开(公告)号: US09540422B2公开(公告)日: 2017-01-10
- 发明人: Jens H. Gundlach , Michael Niederweis , Thomas Z. Butler , Mikhail Pavlenok , Mark A. Troll , Suja Sukumaran
- 申请人: University of Washington , The UAB Research Foundation
- 申请人地址: US WA Seattle US AL Birmingham
- 专利权人: University of Washington,The UAB Research Foundation
- 当前专利权人: University of Washington,The UAB Research Foundation
- 当前专利权人地址: US WA Seattle US AL Birmingham
- 代理机构: Christensen O'Connor Johnson Kindness PLLC
- 主分类号: A61K39/04
- IPC分类号: A61K39/04 ; A61K39/02 ; A61K39/00 ; C07K14/35 ; C12N13/00 ; G01N33/68 ; C12Q1/68 ; G01N27/447 ; G01N33/487
摘要:
Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins. Also provided are bacterial strains capable of inducible Msp porin expression.
公开/授权文献
- US20160137703A1 MSP Nanopores and Related Methods 公开/授权日:2016-05-19
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