System and method of application configuration using DNS-based service discovery, the method including: determining a network domain of a user; retrieving PTR, SRV and TXT records from a DNS server associated with the network domain; enumerating service instances based upon the retrieved PTR, SRV and TXT records; receiving a selection of a service instance from the user; constructing a service instance URL from the selected service instance; attempting to retrieve a settings file by use of the service instance URL; and applying configuration settings from the retrieved settings file.