发明授权
- 专利标题: Bifunctional compounds
- 专利标题(中): 双功能化合物
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申请号: US14880862申请日: 2015-10-12
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公开(公告)号: US09546144B2公开(公告)日: 2017-01-17
- 发明人: Peter Wipf , Joel S. Greenberger , Michael W. Epperly , Melissa M. Sprachman , Julie Pamela Goff
- 申请人: University of Pittsburgh—of the Commonwealth System of Higher Education
- 申请人地址: US PA Pittsburgh
- 专利权人: University of Pittsburgh—Of the Commonwealth System of Higher Education
- 当前专利权人: University of Pittsburgh—Of the Commonwealth System of Higher Education
- 当前专利权人地址: US PA Pittsburgh
- 代理机构: Klarquist Sparkman, LLP
- 主分类号: A61K38/06
- IPC分类号: A61K38/06 ; A61K38/07 ; C07D305/06 ; C07D405/14 ; C07D405/12 ; C07K5/087 ; C07K5/065 ; C07D205/04 ; C07K5/097
摘要:
A compound having the formula: wherein X is S, SO or SO2; one of R1, R2, and R3 is O and the others of R1, R2 and R3 are independently, the same or different, CH2, or CR13 wherein, R13 is an alkyl group, an alkenyl group, an alkynyl group, a trialkylsilyl group, or —(CH2)mOR15, wherein R15 is an alkyl group or an aryl group and m is an integer in the range of 1 to 10, and one of R5, R6, and R7 is O and the others of R5, R6 and R7 are independently, the same or different, CH2, or CR14 wherein, R14 is an alkyl group, an alkenyl group, an alkynyl group, a trialkylsilyl group, or —(CH2)nOR16, wherein R16 is an alkyl group or an aryl group and n is an integer in the range of 1 to 10; R4 and R8 are independently, the same or different, H, an alkyl group, an alkenyl group, an alkynyl group, an aryl group, a heteroaryl group, a C1-C3 alkoxy group, an aryloxy group, or —(CH2)qOR17, wherein R17 is an alkyl group or an aryl group and q is an integer in the range of 1 to 10, provided that R4 is not a C1-C3 alkoxy group or an aryloxy group when R1 or R3 is O and R8 is not a C1-C3 alkoxy group or an aryloxy group when R5 or R7 is O; R9, R10, R11 and R12 are independently, the same or different, H, an alkyl group, an alkenyl group, an alkynyl group, or an aryl group.
公开/授权文献
- US20160176836A1 BIFUNCTIONAL COMPOUNDS 公开/授权日:2016-06-23
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