A method and system for improving the reception of uplink transmissions in a heterogeneous wireless communication system includes a high-power node such as a macro-cell and a low-power node such as a femto-cell or pico-cell. To address an uplink imbalance where a nearby low-power node power controls a UE such that uplink transmissions of an HSDPA control channel are poorly received at the serving cell, an RNC can instruct the UE to boost its uplink transmit power, remove the UE from soft handover, or disable power control of the UE by the low-power node. To address inter-cell interference, the RNC can limit the UE transmit power and/or enable the victim cell to suppress the interference. Further, a common control channel can be used to power control UEs outside of the convention set of UEs available for power control.