Invention Grant
US09556177B2 Substituted 1,3-thiazoles as synthetic intermediates for preparation of Raf kinase inhibitors
有权
取代的1,3-噻唑作为制备Raf激酶抑制剂的合成中间体
- Patent Title: Substituted 1,3-thiazoles as synthetic intermediates for preparation of Raf kinase inhibitors
- Patent Title (中): 取代的1,3-噻唑作为制备Raf激酶抑制剂的合成中间体
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Application No.: US14444007Application Date: 2014-07-28
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Publication No.: US09556177B2Publication Date: 2017-01-31
- Inventor: Weirong Chen , Benjamin Lane , Hairuo Peng
- Applicant: Millennium Pharmaceuticals, Inc. , Sunesis Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge US CA South San Francisco
- Assignee: Millennium Pharmaceuticals, Inc.,Sunesis Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.,Sunesis Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge US CA South San Francisco
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: C07D277/20
- IPC: C07D277/20 ; C07D213/61 ; C07D487/04 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D413/14 ; C07D417/12 ; C07D417/14 ; C07D471/04 ; C07D473/00
Abstract:
The present disclosure provides compounds having Formula II-vi-a: wherein Cy1, Cy2, and A− are defined as set forth in the specification. These compounds are synthetic intermediates used to prepare inhibitors of Raf protein kinase.
Public/Granted literature
- US20150080568A1 COMPOUNDS USEFUL AS RAF KINASE INHIBITORS Public/Granted day:2015-03-19
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