Invention Grant
US09556412B2 Inlet and outlet geometries for a vertical three-stream microfluidic device
有权
用于垂直三流微流体装置的入口和出口几何形状
- Patent Title: Inlet and outlet geometries for a vertical three-stream microfluidic device
- Patent Title (中): 用于垂直三流微流体装置的入口和出口几何形状
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Application No.: US14394693Application Date: 2013-04-17
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Publication No.: US09556412B2Publication Date: 2017-01-31
- Inventor: Allison Hubel , Jacob Hanna
- Applicant: Regents of the University of Minnesota
- Applicant Address: US MN Minneapolis
- Assignee: Regents of the University of Minnesota
- Current Assignee: Regents of the University of Minnesota
- Current Assignee Address: US MN Minneapolis
- Agency: Schwegman Lundberg & Woessner, P.A.
- International Application: PCT/US2013/036933 WO 20130417
- International Announcement: WO2013/158737 WO 20131024
- Main IPC: C12M1/00
- IPC: C12M1/00 ; B01L3/00

Abstract:
An example includes an apparatus for separating cells from a fluid sample, including a plenum, defining: a centrally located top inlet, and respective side outlets disposed below the inlet and to the side of the inlet; and a bottom outlet disposed below the top inlet, to the side of the two or more outlets, wherein the plenum is configured to receive a fluid and cells suspension through the inlet, and direct it to the bottom outlet, against respective side-walls extending between the bottom outlet and the two or more side outlets, and wherein the distance between each of the two or more side outlets and the bottom outlet is selected to encourage cells to exit through the bottom outlet under a force. Lateral/vertical distance between the inlet and side outlets can provide lateral fluid travel, thereby allowing time for gravity to bias cells toward an outlet.
Public/Granted literature
- US20150111241A1 INLET AND OUTLET GEOMETRIES FOR A VERTICAL THREE-STREAM MICROFLUIDIC DEVICE Public/Granted day:2015-04-23
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