Invention Grant
- Patent Title: Opsin-binding ligands, compositions and methods of use
- Patent Title (中): 组氨酸 - 结合配体，组合物和使用方法
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Application No.: US12802898Application Date: 2010-06-16
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Publication No.: US09562022B2Publication Date: 2017-02-07
- Inventor: David S. Garvey , Gregory J. LaRosa , Jeremy R. Greenwood , Mark L. Brewer , Tan Quach , Jamie B. Côté , Judd Berman
- Applicant: David S. Garvey , Gregory J. LaRosa , Jeremy R. Greenwood , Mark L. Brewer , Tan Quach , Jamie B. Côté , Judd Berman
- Applicant Address: US MA Cambridge
- Assignee: BIKAM PHARMACEUTICALS, INC.
- Current Assignee: BIKAM PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Cambridge
- Agency: Troutman Sanders LLP
- Main IPC: C07D279/00
- IPC: C07D279/00 ; C07D295/00 ; C07D243/08 ; C07D207/12 ; C07D207/14 ; C07D295/182 ; C07D295/185 ; C07D295/194 ; C07D491/10 ; C07D493/08
Abstract:
Compounds and compositions of said compounds along with methods of use of compounds are disclosed for treating ophthalmic conditions related to mislocalization of opsin proteins, the misfolding of mutant opsin proteins and the production of toxic visual cycle products that accumulate in the eye. Compounds and compositions useful in the these methods, either alone or in combination with other therapeutic agents, are also described.
Public/Granted literature
- US20110003784A1 Opsin-binding ligands, compositions and methods of use Public/Granted day:2011-01-06
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