Invention Grant
- Patent Title: Compounds that inhibit MCL-1 protein
- Patent Title (中): 抑制MCL-1蛋白的化合物
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Application No.: US14839149Application Date: 2015-08-28
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Publication No.: US09562061B2Publication Date: 2017-02-07
- Inventor: Sean P. Brown , Yunxiao Li , Joshua Taygerly , Marc Vimolratana , Xianghong Wang , Manuel Zancanella
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Joseph F. Reidy
- Main IPC: C07D513/10
- IPC: C07D513/10 ; C07D513/08

Abstract:
Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.
Public/Granted literature
- US20160068545A1 COMPOUNDS THAT INHIBIT MCL-1 PROTEIN Public/Granted day:2016-03-10
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