发明授权
US09562912B2 Method of identifying abnormal cells by expression levels of ETFB
有权
通过ETFB表达水平鉴定异常细胞的方法
- 专利标题: Method of identifying abnormal cells by expression levels of ETFB
- 专利标题(中): 通过ETFB表达水平鉴定异常细胞的方法
-
申请号: US14342774申请日: 2011-12-27
-
公开(公告)号: US09562912B2公开(公告)日: 2017-02-07
- 发明人: Shigenari Hirokawa , Hiroyuki Kitajima , Tomomasa Shimanuki
- 申请人: Shigenari Hirokawa , Hiroyuki Kitajima , Tomomasa Shimanuki
- 申请人地址: JP Tokyo
- 专利权人: POLA PHARMA INC.
- 当前专利权人: POLA PHARMA INC.
- 当前专利权人地址: JP Tokyo
- 代理机构: Knobbe, Martens, Olson & Bear, LLP
- 优先权: JP2011-206582 20110905
- 国际申请: PCT/JP2011/080247 WO 20111227
- 国际公布: WO2013/035209 WO 20130314
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; G01N33/68 ; G01N33/50 ; C12N15/113
摘要:
Provided is a method for identifying and suppressing abnormal growth of fibroblasts at an early stage. Provided is a method for identifying the growth state of fibroblasts using as an index the level of expression of ETFB (electron transfer flavoprotein beta subunit), comprising: judging, in cases where the level of expression of ETFB is high, that there is a high probability that fibroblasts are abnormally growing; and judging, in cases where the level of expression of ETFB is low, that there is a high probability that fibroblasts are normally growing. Further, by inhibition of ETFB, abnormal growth of fibroblasts can be suppressed.
公开/授权文献
信息查询