In a wireless network, a user equipment (UE) can communicate with an Evolved Node B (eNodeB). During at least some times, the UE transmits a data stream to the eNodeB, over one of several available antenna states on the UE. The antenna states can include one or more tuning states for each antenna port on the UE. At predetermined times, which can be periodic, the UE ceases transmission of the data stream, transmits a test signal sequentially over each of its antenna states, receives a signal back from the eNodeB indicating which of the antenna states provides the strongest signal, and switches to the indicated antenna state. After switching, the UE can resume transmission of the data stream over the indicated antenna state. In some examples, the UE can repeat the antenna tuning/retuning process periodically.