Invention Grant
US09575036B2 Method for measuring encapsulation efficiency for hydrophobic actives 有权
测量疏水性活性物质的包封效率的方法

  • Patent Title: Method for measuring encapsulation efficiency for hydrophobic actives
  • Patent Title (中): 测量疏水性活性物质的包封效率的方法
  • Application No.: US14429662
    Application Date: 2013-09-18
  • Publication No.: US09575036B2
    Publication Date: 2017-02-21
  • Inventor: Fanwen ZengBoris Polanuyer
  • Applicant: ROHM AND HAAS COMPANY
  • Applicant Address: US PA Philadelphia
  • Assignee: Rohm and Haas Company
  • Current Assignee: Rohm and Haas Company
  • Current Assignee Address: US PA Philadelphia
  • Agent Edward L. Brant
  • International Application: PCT/US2013/060277 WO 20130918
  • International Announcement: WO2014/047101 WO 20140327
  • Main IPC: G01N30/02
  • IPC: G01N30/02 G01N1/18 A61K8/11
Method for measuring encapsulation efficiency for hydrophobic actives
Abstract:
Described are methods of determining free hydrophobic active in aqueous formulations including the steps of encapsulating a hydrophobic active, preparing a formulation containing encapsulated hydrophobic active, adding a cyclodextrin to the formulation, thereby entraining any free hydrophobic active; and quantifying the amount of free hydrophobic active.
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