An electronic device includes a biometric sensing device connected to a processing channel that includes at least one amplifier having a gain. One or more processing devices is operatively connected to the biometric sensing device and adapted to compensate for signal fixed pattern noise in signals received from the processing channel. The signal fixed pattern noise can include signal measurement variation noise and gain variation noise. The biometric sensing device captures a new image or data, and at least one processing device compensates for the signal fixed pattern noise in the newly captured image or data.