Disclosed are a current zero-cross detection device, zero-cross current signal acquisition circuit and totem pole bridgeless circuit system. The current zero-cross detection device includes a current transformer, first sampling switch, second sampling switch, sampling resister, comparator. The current transformer includes a primary winding and a secondary winding; the primary winding is connected to a circuit to be detected; two ends of the secondary winding are connected respectively to drain electrodes of the first and second sampling switches; source electrodes of first and second sampling switches are connected to ground; two ends of the sampling resistor are connected respectively to the drain electrode and source electrode of the second sampling switch; the negative input end of the comparator is connected to the drain electrode of the second sampling switch, its positive input end is connected to a reference voltage; the first and second sampling switches are in ON or OFF state.