A container sealing system and a container feature are disclosed. The container sealing system includes one or more seals encompassing a container opening, wherein the one or more seals are interlockable or otherwise engageable to seal the container when activated; a first slider head including a male fitting coupled to the one or more seals; and a second slider head coupled to the one or more seals and opposing the first slider head, and including a female fitting for receiving and coupling the male fitting. Actuation of at least one of the slider heads such that the male fitting contacts the female fitting couples the one or more seals encompassing the container opening, sealing the container. The container sealing system may be child-resistant, may be resealable, and/or may include a tamper-indicating feature. The container including the container sealing system may be used for containing, storing, or transporting materials that are not suitable for handling or consumption by a child.