Invention Grant
US09586888B2 Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors 有权
苯基取代的环烷基胺作为单胺再摄取抑制剂

Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors
Abstract:
Phenyl-substituted cyclohexylamine derivatives and method for their synthesis and characterization are disclosed. Use of these compounds to treat/prevent neurological disorders as well as methods for their synthesis are set forth herein. Exemplary compounds of the invention inhibit reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine (e.g., from the synaptic cleft) and modulate one or more monoamine transporter. Pharmaceutical formulations incorporating compounds of the invention are also provided.
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