A low-power wearable controller and associated control method are provided. The wearable controller includes: a processing unit; a memory unit; a peripheral interface unit including a plurality of peripheral interfaces; and a control module, coupled to the processing unit, the memory unit and the peripheral interface unit, wherein the control module is enabled when the wearable controller is operated in a first operation mode, and the control module is disabled when the wearable controller is operated in a second operation mode.