Data processing systems and methods are provided that improve the perceived efficiency of image analysis tools in a digital pathology workflow when challenged by analyzing large size microscopic images. Various embodiments utilize a separation of the image analysis programs into a first automatically executed segment that requires no user interactions for identification and quantification of object data of processed images, and a second interactive segment for accepting user input. User interactions are only applied to the already calculated object data resulting in an improved system response time. A tile-based processing scheme with concurrent processing and generation of object data in a tile-based data format provides further performance improvements of the system.