This application provides a processing method for channel measurement, a base station, and a user equipment, where the method includes: receiving an interference report from a user equipment; and determining, according to the interference report, at least two measurement sets for the user equipment, and notifying the at least two measurement sets to the user equipment. In this application, a measurement set is determined according to an interference report reported by a user equipment, so that the determined measurement set is more adaptive to a current interference situation of the user equipment, and then channel quality of a subframe of the user equipment can be measured accurately.