A leadless cardiac pacing system includes first and second leadless pacing seeds configured to deliver pacing therapy to a first and second location in a patient, respectively. The second seed includes an electrode, a therapy circuit configured to provide electrostimulation energy to the electrode, a communications component, and a power source. The second seed also includes a power manager configured to detect an end-of-life condition associated with the seed and, in response to detecting the end-of-life condition, to communicate a signal that causes the first seed to change from a first operational state to a second operational state, in which the first seed implements one or more operational parameters configured to adapt to a change in an output from the second seed resulting from the second seed entering the end-of-life condition.