Invention Grant
- Patent Title: Use of fusion protein
- Patent Title (中): 使用融合蛋白
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Application No.: US14653276Application Date: 2013-12-05
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Publication No.: US09593151B2Publication Date: 2017-03-14
- Inventor: Changsheng Liu , Wanli Xing , Jing Wang , Jiangchao Qian , Jing Liang
- Applicant: East China University of Science & Technology
- Applicant Address: CN Shanghai
- Assignee: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: CN Shanghai
- Agent Adam Bell; Matthew Kaser
- Priority: CN201210553208 20121218
- International Application: PCT/CN2013/088671 WO 20131205
- International Announcement: WO2014/094546 WO 20140626
- Main IPC: A61K31/18
- IPC: A61K31/18 ; A61K31/664 ; C07K14/51 ; A61K38/18 ; A61K38/19 ; A61K9/00
Abstract:
Disclosed is the use of a fusion protein in drugs for stimulating differentiation of bone marrow mesenchymal stem cells to hematopoietic stem/progenitor cells, or drugs for proliferation of granulocyte hematopoietic progenitor cells. The fusion protein has a sequence as shown in SEQ ID NO: 2 or SEQ ID NO: 4. The drugs can be used for the prevention and/or treatment of (i) hematopoietic dysfunction caused by chemotherapy, (ii) hematopoietic dysfunction caused by radiotherapy, or (iii) leukopenia.
Public/Granted literature
- US20150337025A1 USE OF FUSION PROTEIN Public/Granted day:2015-11-26
Information query
