A control device for a thrust reverser of a turbojet engine nacelle, which includes movable portions actuated by actuators, includes: a first blocking control acting on a motor-actuated system; and a second blocking control acting, mechanically, on the movable portions. The second blocking control may inhibit, when activated, a deployment of the movable portions. The control device further includes a device inhibiting disengagement of the first blocking control when a mechanical control is activated.