Systems, methods and media for managing digital rights and pre-verification of structural integrity in three-dimensional (3D) printing are provided. In one example, a system comprises at least one module, executing on one or more computer processors, to receive a request from a user to print a 3D object by a 3D printer or printing service and receive a conditional authorization from an owner of digital rights in the 3D object to print the 3D object. The conditional authorization can include a printing specification or limitation. The at least one module pre-verifies, for structural integrity once printed by the 3D printer or printing service, a digital model on which the 3D object is based. In response to a received conditional authorization, the at least one module transmits instructions to the 3D printer or printing service to print the 3D object.