- 专利标题: Antibacterial piperidinyl substituted 3,4-dihydro-1H-[1,8]naphthyridinones
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申请号: US14624452申请日: 2015-02-17
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公开(公告)号: US09598407B2公开(公告)日: 2017-03-21
- 发明人: Jerôme Emile Georges Guillemont , David Francis Alain Lançois , Magali Madeleine Simone Motte , Anil Koul , Wendy Mia Albert Balemans
- 申请人: JANSSEN SCIENCES IRELAND UC
- 申请人地址: IE Co, Cork
- 专利权人: Janssen Sciences Ireland UC
- 当前专利权人: Janssen Sciences Ireland UC
- 当前专利权人地址: IE Co, Cork
- 优先权: EP11177116 20110810
- 主分类号: A61K31/4375
- IPC分类号: A61K31/4375 ; C07D221/04 ; C07D471/04
摘要:
The present invention is related to novel compounds of formula (I) that inhibit the activity of the FabI enzyme which are therefore useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.
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