Invention Grant
- Patent Title: Micro-RNAs involved in macular degeneration
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Application No.: US14398330Application Date: 2013-05-02
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Publication No.: US09598694B2Publication Date: 2017-03-21
- Inventor: Shusheng Wang , Eric Olson , Qinbo Zhou
- Applicant: The Board of Regents of the University of Texas System
- Applicant Address: US TX Austin US LA New Orleans
- Assignee: The Board of Regents of the University of Texas System,The Administrators of the Tulane Educational Fund
- Current Assignee: The Board of Regents of the University of Texas System,The Administrators of the Tulane Educational Fund
- Current Assignee Address: US TX Austin US LA New Orleans
- Agency: Parker Highlander PLLC
- International Application: PCT/US2013/039197 WO 20130502
- International Announcement: WO2013/166240 WO 20131107
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K31/7105 ; A61K31/713 ; A61K45/06
Abstract:
The present invention relates to the involvement of miR function in the development of age-related macular degeneration (AMD). It is shown that miR-23, miR-24 and/or miR-27 are involved in pathologic neovascularization in AMD, and that agonism (miR-24) and inhibition (miR23/27) of the function of these molecules blocks events contributing to development and progression of disease.
Public/Granted literature
- US20150087693A1 MICRO-RNAS INVOLVED IN MACULAR DEGENERATION Public/Granted day:2015-03-26
Information query
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