A cache or other cluster is configuration-aware such that initialization and changes to the underlying structure of the cluster can be dynamically updated for use by a client. A client may use a client driver as an intermediary that is responsible for managing the communication with the cluster. For example, a client driver may resolve an alias from a static configuration endpoint to a storage node. The client driver may request an initial configuration from the storage node and then update configuration from one or more storage nodes that store current configuration of the cluster.